Handbook of Clinical Nanomedicine: From Bench to Bedside.pdf
General Science at the nanoscale: Introduction and historical perspective Song, Haur and Wee Nanomedicine: Dynamic integration of nanotechnology with biomedical science Lee, Solanki, Kim, Jung Defining nanotechnology and nanomedicine - big issue in small science Bawa Nano-therapeutics and the future of medicine Bawa, Bawa and Mehra Top ten recent nanomedical advances Swan Nanosystems, Nanodevices and Imaging Tools Nanosizing approaches in drug delivery Chavhan, Petkar and Sawant Design and development of approved nanopharmaceutical products Mansour, Park and Bawa Designing nanocarriers for the effective treatment of cardiovascular diseases Vaidya and Vyas Nanoparticles for multi-modality diagnostic imaging and drug delivery Lockhart and Ho Magnetic nanoparticles in magnetic resonance imaging: A translational push toward theranostics Ortega, Yankeelov and Giorgio Atomic force microscopy for nanomedicine Sharma and Gimzewski Advances in the use of nanomedicine for medical imaging Dearling and Packard Image-based high-content analysis, stem cells and nanomedicines: A novel strategy for drug discovery Solomesky, Adalist and Weil AFM imaging and probing amyloid nanoaggergates Lyubchenko Intracellular transport and unpacking of polyplex nanoparticles Rosenkranz, Khramtsov, Ulasov, Rodichenko and Sobolev Cell and protein interactions with small-scale diamond materials Narayan, Boehm and Monteiro-Riviere Bacterial secretion systems: nanomachines for infection and genetic diversity Shala, Ferarro and Audette Viral nanoparticles: Tools for materials science and biomedicine Steinmetz and Manchester Clinical Applications Polysaccharides as nanomaterials for therapeutics Mizrahy and Peer Diwan Aptamers in clinical trials Kanwar, Roy, Kanwar and Bawa Nanotechnology and the skin barrier: topical and transdermal nanocarrier-based delivery Labouta and Schneider Transdermal immunotherapy with synthetic pathogen-like nanomedicines and its clinical application towards the cure of HIV Lorincz and Lisziewicz Application of nanotechnology in non-invasive topical gene therapy Esabahy, Jimena Loureiro and Foldvari Nanocarriers in the therapy of inflammatory disease Lamprecht Nanomedicine challenges in thrombosis Karagkiozaki Nanomedicine for cardiovascular disease: Potentials and Challenges Karagkiozaki Nanomedicine for acute lung injury/acute respiratory distress syndrome: a shifting paradigm? Sadikot and Rubinstein Multilayered nanoparticles for personalized medicine: translation into clinical markets Prina-Mello Carbon nanotubes as substrates for neuronal growth Menard-Moyon Polymeric nanoparticles for cancer therapeutics Verma, Rosen, Meerasa, Yoffe and Gu Nanotechnology for radiation oncology Sridhar, Berbeco, Cormack, and Makrigiorgos Solid lipid nanoparticles and nanostructured lipid carriers for cancer therapy Uner Nanoparticles for brain cancer therapy Agarwal, Tiwari, Agrawal Complement activation: a capricious immune barrier to nanomedicine clinical application Szebeni Regulatory Issues, Toxicology, Intellectual Property and Nano-Ethics Regulating nanomedicine at the FDA and EPA Hartman, Bawa, Monica Regulatory aspects of nanomedicine in Europe D'Silva Managing environmental and health risks in the nanotechnology industry Huan Toxicity of silicon dioxide nanoparticles in mammalian neural cells Lai, Jaiswal, Lai, Jandhyam, Leung and Bhushan An intellectual property primer for nanomedical researchers and engineers Reese Strategic intellectual property management - building IP portfolios Langer IP Valuation: principles and applications in the nanotechnology industry Kasznik Extending patent term for nanomedical inventions - A nexus between the FDA and the patent system Hopkins Technology transfer: An overview Goldstein Licensing issues in nanotechnology Brougher The Tower of Babel: miscommunication within and about nanomedicine Juliano Clinical nanobioethical problems: a value approach Alvarez-Diaz The audience is the message: nanomedicine as apotheosis or damnatio memoriae Berube
The enormous advances in nanomedicine in the past decade have necessitated a growing need for an authoritative and comprehensive reference source that can be relied upon by scientists, clinicians, students, and industry and policy makers alike. The Handbook of Clinical Nanomedicine: From Bench to Bedside is designed to offer a global perspective on the wonders of nanomedicine. The handbook aims to provide a broad survey of various interconnected topics pertaining to nanomedicine. It is intended to be a stand-alone, easily accessible volume that examines the entire "product wheel" from creation of nanomedical products to final market introduction, all accomplished in a user-friendly format. Specifically, everything from bio-nanomaterials and nanodevices from the R&D stage to patent protection, clinical regulatory aspects, and eventual commercialization is encompassed in this book. In addition to highlighting cutting-edge technologies, the book addresses critical topics such as ethics, safety and toxicity, environmental health, nanoeconomics, business strategy, licensing, intellectual property, FDA law, EPA law, and governmental policy issues. With contributions from international experts, the diverse team of editors has compiled a book that provides a unified perspective to these varied topics. While many books focus on nanomedicine, nanotechnology, or nanoscience, none provide the medical applications of nanotechnology with both a clinical and business angle. Furthermore, most of the currently available books on the market fail to highlight the truly global nature of nanomedicine. The handbook, divided into four sections, provides a comprehensive road map of basic research in nanomedicine as well as clinical applications and commercialization activities. Each of the 45-plus chapters contains 10-20 key words, extensive tables, color figures, future projections, and an extensive list of references. The handbook is an essential reading for the novice and expert alike in fields such as medicine, law, biotechnology, pharmaceutical sciences, engineering, biomedicine, policy, future studies, ethics, intellectual property law, licensing, and toxicology. While bridging the gap between basic biomedical research, engineering, and medicine, the handbook provides an understanding of nanotechnology's use to solve medical problems current applications and their potential regulatory environment and policy issues intellectual property, licensing, and business activities It is clear that the well-known editors have skillfully selected and thoroughly edited each chapter to reflect the most updated information possible. The range of topics covered as well as the international selection of authors is truly impressive. Since the rapidly evolving field of nanomedicine is very diverse and covers physical, chemical, biological, and engineering aspects, the range of the contributing authors accurately reflects this. The book's multidisciplinary approach and an in-depth focus on nanomedicine, pharmaceutical sciences, materials science, biomedical engineering, and biotechnology will attract a global audience. In short, Handbook of Clinical Nanomedicine: From Bench to Bedside promises to be a standard reference text in this expansive and interdisciplinary field. It is a timely addition to the literature on nanosciences and will undoubtedly serve as a catalyst to stimulate interest in this rapidly growing field.