Indole Ring Synthesis: From Natural Products to Drug Discovery.pdf

Indole Ring Synthesis: From Natural Products to Drug Discovery.pdf
 

书籍描述

目录

Chapter 1. Introduction

1. Preview

2. Indole-Containing Natural Products

3. Biological Activity of Indoles

4. Indole-Containing Pharmaceuticals

5. Indole-Containing Materials

6. Indole-Containing Ligands

7. Reviews of Indole Ring Synthesis

References

Chapter 2. The Fischer Indole Synthesis

1. Preview

2. Methods

a. Traditional

b. Metal-Catalyzed

c. Solid Phase Fischer Indolization

d. Other General Methods of Fischer Indole Synthesis

f. Hydrazones

g. Other Fischer Indole Synthesis Variations

3. Applications of Fischer Indolizations

a. Drug Targets

b. Natural Products

c. Materials

d. General

References

Chapter 3. Gassman Indole Synthesis

References

Chapter 4. Bartoli Indole Synthesis

References

Chapter 5. Thyagarajan Indole Synthesis

References

Chapter 6. Julia Indole Synthesis

References

Chapter 7. Miscellaneous Sigmatropic Rearrangements

References

Chapter 8. Madelung Indole Synthesis

References

Chapter 9. Wittig-Madelung Indole Synthesis

References

Chapter 10. Jones-Schmid Indole Synthesis

References

Chapter 11. Couture Indole Synthesis

References

Chapter 12. Wender Indole Synthesis

References

Chapter 13. Smith Indole Synthesis

References

Chapter 14. Kihara Indole Synthesis

References

Chapter 15. Nenitzescu 5-Hydroxyindole Synthesis

References

Chapter 16. Engler-Kita Indole Synthesis

References

Chapter 17. Bailey-Liebeskind-O'Shea Indoline-Indole Synthesis

References

Chapter 18. Wright Indoline Synthesis

References

Chapter 19. Saegusa Indole Synthesis

References

Chapter 20. Ichikawa Indole Synthesis

References

Chapter 21. Miscellaneous Nucleophilic Cyclizations that Form the Indole Ring

References

Chapter 22. Sugasawa Indole Synthesis

References

Electrophilic Cyclization

Chapter 23. Bischler Indole Synthesis

References

Chapter 24. The Nordlander Indole Synthesis

References

Chapter 25. Nitrene Cyclization

References

Chapter 26. Cadogan-Sundberg Indole Synthesis

References

Chapter 27. Sundberg Indole Synthesis

References

Chapter 28. The Hemetsburger Indole Synthesis

References

Chapter 29. Taber Indole Synthesis

References

Chapter 30. Knochel Indole Synthesis

References

Chapter 31. Täuber Carbazole Synthesis

References

Chapter 32. Quéguiner Azacarbazole Synthesis

References

Chapter 33. Iwao Indole Synthesis

References

Chapter 34. Hewson Indole Synthesis

References

Chapter 35. Magnus Indole Synthesis

References

Chapter 36. Feldman Indole Synthesis

References

Chapter 37. Butin Indole Synthesis

References

Chapter 38. Miscellaneous Electrophilic Cyclizations

References

Reductive Cyclization

Chapter 39. Nenitzescu o,-Dinitrostyrene Reductive Cyclization

References

Chapter 40. Reissert Indole Synthesis

References

Chapter 41. Leimgruber-Batcho Indole Synthesis

References

Chapter 42. Pschorr-Hoppe Indole Synthesis

References

Chapter 43. Mąkosza Indole Synthesis

References

Chapter 44. The Rawal Indole Synthesis

References

Chapter 45. The Baeyer-Jackson Indole Synthesis and Miscellaneous Reductive Cyclization Indole Syntheses

References

Oxidative Cyclization

Chapter 46. Watanabe Indole Synthesis

References

Chapter 47. Knölker Carbazole Synthesis

References

Chapter 48. Miscellaneous Oxidative Cyclizations

References

Radical Cyclization

Chapter 49. Fukuyama Indole Synthesis

References

Chapter 50. Other Tin-Mediated Indole Syntheses

References

Chapter 51. The Murphy Indole Synthesis

References

Chapter 52. Miscellaneous Radical-Promoted Indole Syntheses

References

Chapter 53. The Graebe-Ullmann Carbazole-Carboline Synthesis

References

Cycloaddition and Electrocyclization

Chapter 54. Diels-Alder Cycloaddition

References

Chapter 55. Plieninger Indole Synhesis

References

Chapter 56. Photochemical Synthesis of Indoles and Carbazoles

References

Chapter 57. Dipolar Cycloaddition, Anionic, and Electrocyclization Reactions

References

Indoles from Pyrroles

Chapter 58. Electrophilic Cyclization of Pyrrole

References

Chapter 59. Palladium-Catalyzed Cyclization of Pyrroles

References

Chapter 60. Cycloaddition Syntheses from Vinyl Pyrroles

References

Chapter 61. Electrocyclization of Pyrroles

References

Chapter 62. Indoles from Pyrrolo-2,3-quinodimethanes

References

Chapter 63. Indoles via Dehydrogenation of Pyrroles

References

Chapter 64. Miscellaneous Indole Syntheses from Pyrroles

References

Chapter 65. Pyrroles via Arynes

References

Chapter 66. Indoline Dehydrogenation

References

Chapter 67. Indolines to Indoles by Functionalized Elimination

References

Chapter 68. Indolines from Oxindoles, Isatins, and Indoxyls

References

Metal-Catalyzed Indole Synthesis

Chapter 69. Copper-Catalyzed Indole Synthesis

References

Chapter 70. Palladium-Catalyzed Indole Ring Synthesis — Hegedus

References

Chapter 71. Palladium-Catalyzed Indole Ring Synthesis — Mori-Ban-Heck

References

Chapter 72. Palladium-Catalyzed Indole Ring Synthesis — Aryl-Heck

References

Chapter 73. Palladium-Catalyzed Indole Ring Synthesis — Oxidative Cyclization

References

Chapter 74. Palladium-Catalyzed Indole Ring Synthesis — Watanabe-Cenini-Söderberg

References

Chapter 75. Palladium-Catalyzed Indole Ring Synthesis — Yamanaka-Sakamoto-Sonogashira

References

Chapter 76. Palladium-Catalyzed Indole Ring Synthesis — Larock

References

Chapter 77. Palladium-Catalyzed Indole Ring Synthesis — Cacchi

References

Chapter 78. Palladium-Catalyzed Indole Ring Synthesis — Buchwald-Hartwig

References

Chapter 79. Palladium-Catalyzed Indole Ring Synthesis. Miscellaneous

References

Chapter 80. Rhodium-Catalyzed Indole Ring Synthesis

References

Chapter 81. Gold-Catalyzed Indole Ring Synthesis

References

Chapter 82. Ruthenium-Catalyzed Indole Ring Synthesis

References

Chapter 83. Platinum-Catalyzed Indole Ring Synthesis

References

Chapter 84. Silver- and Zinc-Catalyzed Indole Ring Synthesis

References

Chapter 85. Iron-, Iridium-, and Indium-Catalyzed Indole Ring Syntheses

References

Chapter 86. Nickel-, Cobalt-, and Molybdenum-Catalyzed Indole Ring Syntheses

References

Chapter 87. Mercury- and Chromium-Catalyzed Indole Ring Syntheses

References

Chapter 88. Miscellaneous Metal-Catalyzed Indole Ring Syntheses

References

Chapter 89. Miscellaneous Indole Ring Syntheses

References

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