The Neuronal Codes of the Cerebellum.pdf

The Neuronal Codes of the Cerebellum.pdf



The Neuronal Codes of the Cerebellum provides the most updated information on what is known on the topics of the cerebellum’s anatomy and single cell physiology, two areas where there has been a gap in knowledge regarding the specific codes it uses to process information internally and convey commands to other brain regions. This has created difficulties for researchers and clinicians looking to develop an understanding of the mechanisms by which it contributes to behavior and how its dysfunction causes neurological symptoms.

Focused on findings related to the neuronal code used by cerebellar neurons for the representation of behavioral and sensory processes, this edited volume will aid scientists in overcoming that knowledge gap, also serving as the first resource to broadly address the different aspects of spike coding in the cerebellum that focuses on spike train analysis.

  • Compiles current knowledge about functioning of the cerebellum on a cellular basis and how information is encoded in the cerebellum
  • Highlights findings related to the neuronal code used by cerebellar neurons for the representation of behavioral and sensory processes
  • Contents include an introduction to the cerebellum and experimental/theoretical techniques, as well as the function of cerebral coding during disorder, learning, behavior generation, motor behavior, and more
  • Bridges the gap for cerebellar researchers between single cell biophysics/anatomic studies and behavioral studies
  • Incorporates various in vivo approaches with different behavioral paradigms in primates and rodents, modeling studies of coding, and in vitro approaches

Associate Professor for UTHSC’s Dept. of Anatomy and Neurobiology, as well as a Visiting Scientist at The Salk Institute for Biological Studies and the Howard Hughes Medical Institute. Dr. Heck's primary research foci are the neuronal foundations of motor/cognitive brain functions and their disorders and the role of coordinated dynamic brain activity in normal and pathological brain function. He serves as Associate Editor for Frontiers in Systems Neuroscience, Review Editor for Frontiers in Neurogenomics, and Editorial Board member for Neuroscience. He was Organizer/Chair for the 2013 SFN symposium on Neuronal Codes and has authored numerous journal articles and book chapters on topics directly related to the proposed.


1. Signaling of predictive and feedback information in Purkinje cell simple spike activity   2. DCN rebound firing in vivo: Much ado about almost nothing?   3. Spatio-temporal aspects of cerebellar coding during learning

4. How the vestibulo-cerebellum builds an internal model of self-motion

5. Modeling the generation of cerebellar nuclear spike output

6. Cerebro-cerebellar loops in the rodent brain

7. Cerebellar neuronal codes - perspectives from intracellular analysis in vivo

8. The role of the cerebellum in optimizing saccades

9. Coordination of reaching movements: Cerebellar interactions with motor cortex

10. The role of synchrony and oscillatory neuronal activity in cerebellar control of behavior

11. Single neuron and network computation in realistic models of the cerebellar cortex


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